pdeonline.org

Robots.txt Information

Robot	Path	Permission
GoogleBot	/	✔
BingBot	/	✔
BaiduSpider	/	✔
YandexBot	/	✔

Meta Tags

Title	PDE
Description	Ensure that every individual with PDE is diagnosed and treated early and improve treatment in such way that every affected individual’s outcome is
Keywords	N/A

Server Information

WebSite	pdeonline.org
Host IP	65.254.248.142
Location	United States

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pdeonline.org Valuation

US$271,061

Last updated: 2023-05-16 06:58:53

pdeonline.org has Semrush global rank of 39,047,744. pdeonline.org has an estimated worth of US$ 271,061, based on its estimated Ads revenue. pdeonline.org receives approximately 31,277 unique visitors each day. Its web server is located in United States, with IP address 65.254.248.142. According to SiteAdvisor, pdeonline.org is safe to visit.

Traffic & Worth Estimates

Purchase/Sale Value	US$271,061
Daily Ads Revenue	US$251
Monthly Ads Revenue	US$7,507
Yearly Ads Revenue	US$90,076
Daily Unique Visitors	2,086
Note: All traffic and earnings values are estimates.

DNS Records

Host	Type	TTL	Data
pdeonline.org.	A	3600	IP: 65.254.248.142
pdeonline.org.	NS	3600	NS Record: ns1.fatcow.com.
pdeonline.org.	NS	3600	NS Record: ns2.fatcow.com.
pdeonline.org.	MX	3600	MX Record: 30 mx.pdeonline.org.
pdeonline.org.	TXT	3600	TXT Record: v=spf1 ip4:38.113.1.0/24 ip4:38.113.20.0/24 ip4:65.254.224.0/19 ?all

HtmlToTextCheckTime:2023-05-16 06:58:53

Home PDE Registry For Professionals Ongoing Research PDE Consortium Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is a rare -yet treatable- inherited metabolic disorder. Recent studies have shown an incidence of 1:65 000 to 1:250 000 live births. The disease is characterized by intractable seizures that, in general, do not respond to conventional antiepileptic medications, but are often controlled by daily high doses of vitamin B6 (pyridoxine). However, even with early diagnosis and B6 treatment, outcomes are often poor; 80% of these children still suffer developmental delay and intellectual disability. Ongoing neurotoxicity despite vitamin B6 treatment may explain these poor outcomes. Antiquitin (ATQ) or the ALDH7A1 gene (see Gene Reviews or OMIM for details), encodes an enzyme in the lysine degradation pathway named α-aminoadipic semi-aldehyde dehydrogenase. Deficiency of this enzyme leads to accumulation of chemical substances -called AASA, P6C and pipecolic acid- that are neurotoxic

HTTP Headers

HTTP/1.1 302 Found
Date: Thu, 20 Jan 2022 09:57:20 GMT
Content-Type: text/html; charset=iso-8859-1
Connection: keep-alive
Server: Apache/2
Location: https://pdeonline.org/
Cache-Control: max-age=3600
Expires: Thu, 20 Jan 2022 10:57:20 GMT
Age: 0

HTTP/1.1 200 OK
Date: Thu, 20 Jan 2022 09:57:21 GMT
Content-Type: text/html
Content-Length: 28253
Connection: keep-alive
Server: Apache/2
Last-Modified: Fri, 07 May 2021 13:26:02 GMT
Accept-Ranges: bytes
Cache-Control: max-age=3600
Etag: "6e5d-5c1bd5e8bad57"
Expires: Thu, 20 Jan 2022 10:57:21 GMT
Age: 0

pdeonline.org Whois Information

Domain Name: PDEONLINE.ORG
Registry Domain ID: D160263849-LROR
Registrar WHOIS Server: whois.domain.com
Registrar URL: www.domain.com
Updated Date: 2021-09-13T14:13:05Z
Creation Date: 2010-09-28T17:32:12Z
Registry Expiry Date: 2022-09-28T17:32:12Z
Registrar: Domain.com, LLC
Registrar IANA ID: 886
Registrar Abuse Contact Email: compliance@domain-inc.net
Registrar Abuse Contact Phone: +1.6022262389
Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited
Domain Status: clientUpdateProhibited https://icann.org/epp#clientUpdateProhibited
Registrant State/Province: British Columbia
Registrant Country: CA
Name Server: NS1.FATCOW.COM
Name Server: NS2.FATCOW.COM
DNSSEC: unsigned
URL of the ICANN Whois Inaccuracy Complaint Form https://www.icann.org/wicf/)
>>> Last update of WHOIS database: 2022-01-20T11:35:39Z <<<

pdeonline.org valuation and analysis